Skip to main content

Table 2 Effect of topical application of the ointment formulated from 80 % methanol extract of the rhizomes of Rumex abyssinicus on wound contraction of excision wound model in mice

From: Evaluation of wound healing and anti-inflammatory activity of the rhizomes of Rumex abyssinicus J. (Polygonaceae) in mice

Group

Wound area (mm2) on post-wounding days

3

5

7

9

11

13

15

SO

234.2 ± 11.8

202.0 ± 10.6

159.1 ± 13.0

110.0 ± 8.5

33.5 ± 5

20.5 ± 2.7

9.2 ± 3.0

5 % HEO

179.3 ± 23.3

150 ± 15.0

80.2 ± 21.7a2

27.3 ± 11.4a2

10 ± 6a2

2 ± 1.4a3

0a2

10 % HEO

82.4 ± 8.1 a3,c2

72.67 ± 9.2a3,c2

39.1 ± 8.1a3

11.0 ± 3.0a3

1.8 ± .5a3

0a3

-

NFO

130.7 ± 17.0a2

108.5 ± 17.4a3

54.5 ± 10.7a3

17.2 ± 4.8a3

4.8 ± 2a3

1.67 ± 1.3a3

0a2

  1. n = 6 animals in each group; Values are expressed as mean ± SEM and analyzed by one way ANOVA followed by tuckey post hoc test; SO, simple ointment base; HEO, hydroalcoholic extract ointment; NFO, nitrofurazone ointment;.numbers (3-15) refer days where measurment was taken following wound creation; 0 values refer day where complete healing was achieved; aagainst control, cagainst 5 % (w/w) hydroalcoholic extract; 2p < 0.01, 3p < 0.001