Phytochemicals, antioxidant, antinociceptive and anti-inflammatory potential of the aqueous extract of Teucrium stocksianum bioss

Table 5 Effect of AETS 100, 200 and 300 mg/kg in tail immersion test

Samples/standard	Dose mg/kg	Tail withdrawing time in sec
Samples/standard	Dose mg/kg	0 min	30 min	60 min	90 min	120 min
Normal saline	10 ml/kg	3.35 ± 0.11	3.48 ± 0.16	3.22 ± 0.032	3.39 ± 0.20	3.34 ± 0.19
AETS	100 mg/kg	3.35 ± 0.04^n.s	3.61 ± 1.03 ^n.s	4.02 ± 1.03*	3.96 ± 0.4*	3.76 ± 1.04 *
	200 mg/kg	3.36 ± 1.34 ^n.s	4.19 ± 1.07*	4.55 ± 0.07**	4.48 ± 0.1**	4.20 ± 2.10**
	300 mg/kg	3.37 ± 0.4 ^n.s	4.80 ± 0.21*	5.36 ± 0.11**	5.30 ± 0.12**	5.03 ± 0.10**
Tramadol^R	30 mg/kg	3.5 ± 0.20 ^n.s	4.99 ± 1.33**	5.69 ± 0.02**	5.49 ± 0.06**	5.39 ± 0.05**
Antinociceptive effect of AETS and Tramadol^R antagonized by Naloxone
AETS	300 mg/kg	3.37 ± 1.05 ^n.s	4.10 ± 2.10 ^n.s	4.13 ± 1.07 ^n.s	4.20 ± 1.05 ^n.s	4.26 ± 1.70 ^n.s
Tramadol^R	30 mg/kg	3.38 ± 1.04 ^n.s	3.75 ± 2.41 ^n.s	3.72 ± 1.50 ^n.s	3.75 ± 1.02 ^n.s	3.70 ± 1.04 ^n.s

Values expressed as mean ± SEM, The data was analyzed by ANOVA followed by Dunnett’s test, n.s shows statistically non significant values, **p <0.01 and *p <0.05 vs. control group (n = 6)

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