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Table 2 Drug prescriptions and cost of drugs 90 and 180 days before the first observed inpatient visit with diagnosis F43 for the integrative care and conventional care cohorts

From: Usage and cost of first-line drugs for patients referred to inpatient anthroposophic integrative care or inpatient conventional care for stress-related mental disorders—a register based study

  Integrative Care (N = 161) Conventional Care (N = 1571) Statistical difference (P-value)
DDD/patient
 ATC-N05A 90-days before 0.8 (−0.1 to 1.7) 2.9 (2.1 to 3.8) <0.001
 ATC-N05B 90-days before 26.5 (16.6 to 36.3) 32.3 (27.9 to 36.7) 0.287
 ATC-N05C 90-days before 5.7 (3.5 to 7.9) 11.9 (10.5 to 13.3) <0.001
 ATC-N06A 90-days before 16.6 (9.6 to 23.7) 21.0 (18.2 to 32.8) 0.260
 ATC-N05A 180 days before 1.3 (−0.01 to 2.7) 5.1 (3.7 to 6.5) <0.001
 ATC-N05B 180 days before 41.4 (25.8 to 57.1) 54.2 (46.4 to 61.9) 0.150
 ATC-N05C 180 days before 10.7 (6.9 to 14.5) 20.6 (18.1 to 23.0) <0.001
 ATC-N06A 180 days before 33.5 (20.1 to 46.7) 37.3 (32.6 to 42.0) 0.592
Cost/patient (EUR)
 ATC-N05A 90-days before 5.4 (−0.3 to 11.1) 19.4 (13.8 to 24.9) <0.001
 ATC-N05B 90-days before 4.8 (2.9 to 6.6) 6.4 (5.5 to 7.2) 0.133
 ATC-N05C 90-days before 4.9 (3.0 to 6.8) 8.4 (7.4 to 9.4) 0.002
 ATC-N06A 90-days before 27.5 (14.6 to 40.4) 24.8 (21.3 to 28.2) 0.699
 ATC-N05A 180 days before 6.8 (−0.3 to 13.9) 36.5 (26.9 to 46.2) <0.001
 ATC-N05B 180 days before 7.6 (4.5 to 10.7) 11.4 (9.8 to 13.0) 0.036
 ATC-N05C 180 days before 8.2 (5.3 to 11.2) 14.7 (12.8 to 16.5) <0.001
 ATC-N06A 180 days before 50.3 (28.5 to 72.1) 46.1 (40.3 to 51.9) 0.722
  1. DDD, Defined daily dose. EUR, euro. Drug categories according to the Anatomical Therapeutic Chemical (ATC) classification system: N05A, antipsychotics; N05B, anxiolytics; N05C, hypnotics and sedatives; and N06A, antidepressants. Average (95 % confidence interval) values. Analyses by t-tests (two tailed)