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Table 4 The changing of antioxidative enzymes levels (ΔAOE) after 4 weeks of treatment (AOE at week 4 - AOE at baseline)

From: A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury

 

ΔAOE after 4 weeks of treatment

 

Silymarin

Placebo

p-value

SODa (%)

−0.20 (−4.0, 6.4)

−4.41 (−6.0, 1.8)

0.027

Glutathionea (ng/ul)

−0.09 (−0.3, 0.0)

−011 (−0.2, 0.0)

0.83

MDAa (nmol/L)

−0.14 (−13.5, 17.1)

−9.74 (−23.8, 6.0)

0.22

  1. AOE, Antioxidative enzymes; SOD, superoxide; MDA, malondialdehyde
  2. aΔAOE reported as median (interquartile range)