From: A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury
ΔAOE after 4 weeks of treatment
Silymarin
Placebo
p-value
SODa (%)
−0.20 (−4.0, 6.4)
−4.41 (−6.0, 1.8)
0.027
Glutathionea (ng/ul)
−0.09 (−0.3, 0.0)
−011 (−0.2, 0.0)
0.83
MDAa (nmol/L)
−0.14 (−13.5, 17.1)
−9.74 (−23.8, 6.0)
0.22