Silymarin | Placebo | p-value | |
---|---|---|---|
(N = 27) | (N = 28) | ||
Male (n, %) | 10 (37.0) | 12 (42.9) | 0.785 |
Age (years) | 56.0 (15, 78) | 51.5 (21, 83) | 0.721 |
BMI (kg/m2) | 21.1 (14.1, 25.4) | 21.0 (15.8, 27.0) | 0.773 |
Dose of Isoniazid (mg/kg) | 5.5 (4.0, 9.0) | 5.7 (4.5, 7.7) | 0.968 |
Dose of rifampicin (mg/kg) | 10.4 (8.0, 14.0) | 10.3 (9.0, 14.0) | 0.965 |
Dose of pyrazinamide (mg/kg) | 23.1 (18.6, 29.1) | 23.8 (17.8, 58.0) | 0.282 |
Dose of ethambutol (mg/kg) | 18.5 (13.3, 24.9) | 18.5 (12.7, 27.8) | 0.859 |
Liver function tests | |||
ALT (IU/L) | 29 (15, 66) | 31 (11, 86) | 0.639 |
AST (IU/L) | 20 (13, 106) | 25.5 (14, 56) | 0.087 |
ALP (IU/L) | 85 (37, 449) | 89.5 (55, 508) | 0.736 |
GGT (IU/L) | 42 (17, 430) | 52.5 (14, 510) | 0.443 |
TP (g/L) | 78.1 (50.5, 91.5) | 76.0 (56.1, 99.4) | 0.452 |
Alb (g/L) | 35.7 (23.0, 42.0) | 33.0 (16.7, 43.8) | 0.639 |
TB (mg/dl) | 0.5 (0.3, 1.9) | 0.6 (0.2, 1.4) | 0.285 |
DB (mg/dl) | 0.2 (0.1, 0.7) | 0.3 (0.1, 5.0) | 0.015 |