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Table 2 Effect of methanol extract of P. foetida on alcohol-induced gastric ulcer in rats

From: Gastroprotective mechanism of Paederia foetida Linn. (Rubiaceae) – a popular edible plant used by the tribal community of North-East India

Treatment

Ulcer score

% of ulcer protection

Group 1 (5 ml distilled water/kg, p.o.)

2.0 ± 0.12

-

Group 2 (5 ml distilled water + 70 % ethanol, 10 ml/kg, p.o.)

3.70 ± 0.49 α

-

Group 3 MeOH PF (100 mg/kg)

1.40 ± 0.29*

59.45

Group 4 MeOH PF (200 mg/kg)

1.0 ± 0.31*

72.97

Group 5 Sucralfate (100 mg/kg, p.o.)

0.70 ± 0.12*

81.08

  1. MeOH PF= methanolic extract of Paederia foetida; n=5; Data = Mean±SEM; αP<0.05 (Group1 Vs Group2); *P<0.05, (Group 2 Vs Group 3, 4 & 5)