Fig. 2

Renal histology after treatment with or without AC and metformin. a Pathological features of the left kidney tissue stained with H&E and Masson stain (orginal magnification 400×). Each photomicrograph represented the pathological feature of four rats from each group. b Matrix expansion and area of fibrosis among the groups were semiquantitatively analyzed. Values were expressed as mean ± SEM (n = 4). #P < 0.01 versus normal group; *P < 0.05 versus control group; **P < 0.01 versus control group