Fig. 1From: TRPV1 channel inhibition contributes to the antinociceptive effects of Croton macrostachyus extract in miceEffects of oral administration of the methanol/methylene chloride extract of the stem bark of Croton macrostachyus (MECM) on the mechanical hyperalgesia induced by von Frey hair (0.4 g) in CFA (20 μl/paw) inflamed mice paw. In persistent treatment, response to pain was evaluated before the treatment of the day, when given. B = basal response to mechanical stimulation. N = 5; ap < 0.05; bp < 0.01; cp < 0.001 significantly different compared to vehicle (ANOVA two way and Bonferoni as post hoc test)Back to article page