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Table 6 Anti-inflammatory activity of the resin of Commiphora guidottii on carrageenan-induced mice paw oedema

From: Evaluation of the wound healing property of Commiphora guidottii Chiov. ex. Guid.

Test substance

Dose (mg/kg)

Percent oedema inhibition

  

1 h

2 h

3 h

4 h

 

150

9.84 ± 0.02

32.86 ± 0.04*

36.23 ± 0.05*

53.85 ± 0.03*

Resin

300

21.16 ± 0.007*

44.98 ± 0.005*

54.83 ± 0.005*

60.05 ± 0.009*

 

600

17.20 ± 0.006*

41.10 ± 0.007*

52.90 ± 0.008*

65.44 ± 0.008*

Indomthacin

10

27.78 ± 0.008*

55.00 ± 0.006*

68.84 ± 0.008*

86.52 ± 0.006*

Vehicle

-

19.05 ± 0.002

30.14 ± 0.006

26.06 ± 0.005

25.00 ± 0.006

  1. *The mean value is significant (p < 0.001) when compared with the negative control group; N = 6; Results are expressed as mean ± SEM