| |
Vehicle
|
HCD
|
CCGG-1X
|
CCGG-2X
|
CCGG-5X
|
|---|
| |
Mean
|
SEM
|
Mean
|
SEM
|
Mean
|
SEM
|
Mean
|
SEM
|
Mean
|
SEM
|
|---|
|
Liver (mg/g)
| | | | | | | | | | |
|
TG
|
142.3***
|
17.1
|
373.4
|
27.6
|
199.8***
|
21.6
|
201.8***
|
24.4
|
208.5***
|
23.0
|
|
Cholesterol
|
0.36***
|
0.02
|
2.33
|
0.38
|
1.50*
|
0.13
|
1.16**
|
0.12
|
0.82***
|
0.62
|
|
Faeces (mg/g)
| | | | | | | | | | |
|
TG
|
21.8
|
2.1
|
27.8
|
2.2
|
37.6
|
3.8
|
37.3
|
1.9
|
17.8
|
2.1
|
|
Cholesterol
|
1.63***
|
0.05
|
2.47
|
0.09
|
2.38
|
0.70
|
1.97**
|
0.79
|
2.21
|
0.13
|
|
Bile acid
|
3.74**
|
0.26
|
6.85
|
0.46
|
9.39*
|
0.71
|
9.36*
|
0.32
|
8.91
|
0.67
|
- Values are expressed as mean ± SEM. Statistical significance was determined using the one-way ANOVA with Tukey’s posttest
- *P < 0.05, **P < 0.01, ***P < 0.001 compared with HCD
- Vehicle; vehicle control, HCD; high-cholesterol diet control, CCGG-1X; high-cholesterol diet with 311 mg/kg/d of CCGG, CCGG-2X; high-cholesterol diet with 622 mg/kg/d of CCGG, CCGG-5X; high-cholesterol diet with 1555 mg/kg/d of CCGG
- TG; triglycerides
