Table 5 Micronucleus test in mice following a single oral dose of ORS
From: Genotoxicity evaluation of Oryeong-san water extract using in vitro and in vivo tests
Group | Vehicle control | ORSE | ORSE | ORSE | Positive control |
|---|---|---|---|---|---|
Dose (mg/kg) | 0 | 500 | 1000 | 2000 | 70 |
MNPCE/2000PCEs (Mean ± S.D) | 0.67 ± 0.58 | 0.33 ± 0.58 | 2.00 ± 1.00 | 1.33 ± 0.58 | 50.00a ± 13.89 |
PCE/(PCE + NCE) (Mean ± S.D) | 0.60 ± 0.06 | 0.63 ± 0.04 | 0.58 ± 0.07 | 0.55 ± 0.12 | 0.49a ± 0.03 |
Number of animals | 3 | 3 | 3 | 3 | 3 |