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Table 4 Body weight changes of Micronucleus test in mice following administration of ORSE

From: Genotoxicity evaluation of Oryeong-san water extract using in vitro and in vivo tests

Group Vehicle control ORSE ORSE ORSE Positive control (cyclophosphamide monohydrate)
Dose (mg/kg) 0 500 1000 2000 70
Day 1 (Mean ± S.D) 35.9 ± 1.31 37.3 ± 2.34 36.9 ± 1.31 37.2 ± 2.41 37.0 ± 1.93a)
Day 2 (Mean ± S.D) 36.0 ± 1.91 37.3 ± 2.23 36.9 ± 1.48 37.1 ± 2.44 37.7 ± 2.26
Day 3 (Mean ± S.D) 35.5 ± 1.80 37.3 ± 2.46 37.3 ± 1.51 37.4 ± 2.52 37.4 ± 2.64