Table 4 Body weight changes of Micronucleus test in mice following administration of ORSE
From: Genotoxicity evaluation of Oryeong-san water extract using in vitro and in vivo tests
Group | Vehicle control | ORSE | ORSE | ORSE | Positive control (cyclophosphamide monohydrate) |
|---|---|---|---|---|---|
Dose (mg/kg) | 0 | 500 | 1000 | 2000 | 70 |
Day 1 (Mean ± S.D) | 35.9 ± 1.31 | 37.3 ± 2.34 | 36.9 ± 1.31 | 37.2 ± 2.41 | 37.0 ± 1.93a) |
Day 2 (Mean ± S.D) | 36.0 ± 1.91 | 37.3 ± 2.23 | 36.9 ± 1.48 | 37.1 ± 2.44 | 37.7 ± 2.26 |
Day 3 (Mean ± S.D) | 35.5 ± 1.80 | 37.3 ± 2.46 | 37.3 ± 1.51 | 37.4 ± 2.52 | 37.4 ± 2.64 |