Evaluating the antidiabetic effects of Chinese herbal medicine: Xiao-Ke-An in 3T3-L1 cells and KKAy mice using both conventional and holistic omics approaches

Table 2 Effect of XKA on tissue weight in diabetic KKAy mice

	C57BL/6J	KKAy	KKAy + XKA-H	KKAy + XKA-L	KKAy + MET
Liver (g)	1.03 ± 0.12	2.11 ± 0.35^##	1.95 ± 0.62	1.82 ± 0.46	1.91 ± 0.30
Relative liver weight	0.042 ± 0.002	0.058 ± 0.007^##	0.051 ± 0.011	0.049 ± 0.010	0.051 ± 0.007
Epidydimal fat pad (g)	0.23 ± 0.05	1.10 ± 0.23^##	1.23 ± 0.22	1.29 ± 0.30	1.28 ± 0.38
Relative epidydimal fat weight	0.010 ± 0.002	0.030 ± 0.006^##	0.033 ± 0.005	0.035 ± 0.008	0.034 ± 0.010
Perirenal fat (g)	0.05 ± 0.02	0.49 ± 0.14^##	0.57 ± 0.19	0.58 ± 0.13	0.56 ± 0.16
Relative perirenal fat weight	0.002 ± 0.001	0.014 ± 0.004^##	0.015 ± 0.004	0.016 ± 0.004	0.015 ± 0.004
Spleen (g)	0.07 ± 0.01	0.12 ± 0.04^##	0.10 ± 0.02	0.10 ± 0.03	0.10 ± 0.01
Relative spleen weight	0.0027 ± 0.0004	0.0033 ± 0.0007^#	0.0028 ± 0.0004	0.0026 ± 0.0007^*	0.0026 ± 0.0003^*
Kidney (g)	0.33 ± 0.04	0.47 ± 0.08^##	0.44 ± 0.07	0.42 ± 0.04	0.42 ± 0.04
Relative kidney weight	0.014 ± 0.001	0.013 ± 0.001	0.012 ± 0.001	0.012 ± 0.001^*	0.011 ± 0.001^**
Heart (g)	0.13 ± 0.02	0.15 ± 0.03	0.15 ± 0.02	0.14 ± 0.01	0.15 ± 0.02
Relative heart weight	0.005 ± 0.001	0.004 ± 0.001^##	0.004 ± 0.001	0.004 ± 0.000	0.004 ± 0.001

ISSN: 2662-7671