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Table 2 Effect of XKA on tissue weight in diabetic KKAy mice

From: Evaluating the antidiabetic effects of Chinese herbal medicine: Xiao-Ke-An in 3T3-L1 cells and KKAy mice using both conventional and holistic omics approaches

  C57BL/6J KKAy KKAy + XKA-H KKAy + XKA-L KKAy + MET
Liver (g) 1.03 ± 0.12 2.11 ± 0.35## 1.95 ± 0.62 1.82 ± 0.46 1.91 ± 0.30
Relative liver weight 0.042 ± 0.002 0.058 ± 0.007## 0.051 ± 0.011 0.049 ± 0.010 0.051 ± 0.007
Epidydimal fat pad (g) 0.23 ± 0.05 1.10 ± 0.23## 1.23 ± 0.22 1.29 ± 0.30 1.28 ± 0.38
Relative epidydimal fat weight 0.010 ± 0.002 0.030 ± 0.006## 0.033 ± 0.005 0.035 ± 0.008 0.034 ± 0.010
Perirenal fat (g) 0.05 ± 0.02 0.49 ± 0.14## 0.57 ± 0.19 0.58 ± 0.13 0.56 ± 0.16
Relative perirenal fat weight 0.002 ± 0.001 0.014 ± 0.004## 0.015 ± 0.004 0.016 ± 0.004 0.015 ± 0.004
Spleen (g) 0.07 ± 0.01 0.12 ± 0.04## 0.10 ± 0.02 0.10 ± 0.03 0.10 ± 0.01
Relative spleen weight 0.0027 ± 0.0004 0.0033 ± 0.0007# 0.0028 ± 0.0004 0.0026 ± 0.0007* 0.0026 ± 0.0003*
Kidney (g) 0.33 ± 0.04 0.47 ± 0.08## 0.44 ± 0.07 0.42 ± 0.04 0.42 ± 0.04
Relative kidney weight 0.014 ± 0.001 0.013 ± 0.001 0.012 ± 0.001 0.012 ± 0.001* 0.011 ± 0.001**
Heart (g) 0.13 ± 0.02 0.15 ± 0.03 0.15 ± 0.02 0.14 ± 0.01 0.15 ± 0.02
Relative heart weight 0.005 ± 0.001 0.004 ± 0.001## 0.004 ± 0.001 0.004 ± 0.000 0.004 ± 0.001
  1. All values are means ± SD (n = 10–11)
  2. #p < 0.05 vs. C57BL/6J mice
  3. ##p < 0.01 vs. C57BL/6J mice
  4. *p < 0.05 vs. KKAy mice
  5. **p < 0.01 vs. KKAy mice