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Table 6 Subchronic effect of S.nigra aqueous extract (Elder), Kaempferol (KMF) on body weights in alloxan-induced diabetic mice (n = 7)

From: Acute and subchronic in-vivo effects of Ferula hermonis L. and Sambucus nigra L. and their potential active isolates in a diabetic mouse model of neuropathic pain

Group

Dose (mg/kg)

Mean body weight ± S.E.M. (gm)

  

1st day

3rd day

5th day

8th day

Control

__

25.90 ± 0.50

26.00 ± 0.60

26.01 ± 0.97

25.09 ± 0.70

Diabetic controla

__

28.68 ± 0.70

27.10 ± 0.20

27.15 ± 0.80

27.10 ± 0.50

GBb

5

22.90 ± 0.70

28.17 ± 1.70

28.54 ± 0.40

30.37 ± 1.10*

Elderb

50

27.10 ± 1.30

28.90 ± 3.10

29.52 ± 2.10

29.91 ± 1.20*

Elderb

100

27.50 ± 1.70

27.83 ± 2.70

28.90 ± 1.70

30.10 ± 1.50*

Elderb

200

27.00 ± 1.50

27.50 ± 2.10

28.10 ± 1.50

30.50 ± 1.40*

KMFb

16

20.50 ± 1.50

21.80 ± 1.30

22.45 ± 1.10

22.64 ± 1.70*

KMFb

32

22.33 ± 1.30

22.81 ± 1.70

23.91 ± 1.40

25.13 ± 1.20*

KMFb

64

22.11 ± 1.60

22.94 ± 1.80

23.54 ± 1.80

25.64 ± 1.20*

  1. S.E.M. standard error of the mean
  2. *p < 0.05 significant from the control animals
  3. aCompared to vehicle control
  4. bCompared to diabetic control