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Table 4 Subchronic effect of S.nigra aqueous extract (Elder), Kaempferol (KMF) on blood glucose of alloxan-induced diabetic mice (n = 7)

From: Acute and subchronic in-vivo effects of Ferula hermonis L. and Sambucus nigra L. and their potential active isolates in a diabetic mouse model of neuropathic pain

Group

Dose (mg/kg)

Mean blood glucose concentration ± S.E.M. (mg/dL)

 
  

1st day

3rd day

5th day

8th day

Control

__

107.90 ± 2.50

109.80 ± 3.60

108.56 ± 3.20

109.50 ± 3.70

Diabetic controla

__

207.79 ± 5.60***

214.93 ± 4.50***

209.91 ± 9.70***

210.55 ± 7.30***

GBb

5

186.70 ± 3.70

179.53 ± 2.90

161.54 ± 2.40**

171.97 ± 3.10

Elder

50

143.18 ± 1.30

127.89 ± 3.10

119.32 ± 2.50*

123.13 ± 1.30

Elder

100

144.17 ± 1.70

128.52 ± 2.70

124.44 ± 2.70

113.33 ± 1.50*

Elder

200

142.12 ± 1.50

122.76 ± 2.10

120.89 ± 2.60

110.13 ± 1.60*

KMF

16

156.86 ± 2.10

153.86 ± 2.30

151.34 ± 1.10

149.67 ± 2.90*

KMF

32

140.30 ± 2.40

141.30 ± 2.80

142.60 ± 1.30

139.41 ± 2.20*

KMF

64

142.68 ± 1.40

137.25 ± 1.70

132.55 ± 2.00

128.65 ± 2.50*

  1. S.E.M. standard error of the mean
  2. *p < 0.05 significant from the control animals
  3. **p < 0.01 significant from the control animals
  4. ***p < 0.001 significant from the control animals
  5. aCompared to vehicle control
  6. bCompared to diabetic control