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Table 4 Effect of turmeric on the serum levels of ALT, AST, ALP, Bilirubin, ALB and TP

From: Pre-administration of turmeric prevents methotrexate-induced liver toxicity and oxidative stress

Groups ALT AST ALP Bilirubin ALB TP
(U/L) (U/L) (IU/L) (mg/dl) (g/dl) (g/dl)
Control 36.53 ± 2.1 51 ± 2.57 186.59 ± 8.68 0.81 ± 0.04 3.67 ± 0.28 6.65 ± 0.55
TUR (100mgkg−1) 34.43 ± 0.18 50.59 ± 2.3 188.43 ± 8.54 0.83 ± 0.06 3.44 ± 0.42 6.82 ± 0.59
TUR (200mgkg−1) 33.9 ± 0.45 49.26 ± 0.36 184.99 ± 8.62 0.85 ± 0.05 3.42 ± 0.54 7.05 ± 0.69
MTX (20mgkg−1) 49.91 ± 2.11a 74.83 ± 3.89a 276.61 ± 10.56a 1.46 ± 0.1a 2.36 ± 0.37a 4.28 ± 0.41a
TUR (100mgkg−1) + MTX 42.42 ± 1.32a 63.48 ± 0.25a 226.78 ± 9.25a 1.21 ± 0.08a 2.9 ± 0.2a 5.48 ± 0.46a
TUR (200mgkg−1) + MTX 39.07 ± 0.4b 57.83 ± 0.31b 209.42 ± 8.7b 0.88 ± 0.07b 3.48 ± 0.38b 6.15 ± 0.57b
  1. Values are shown as mean ± S.D.
  2. TUR Turmeric, MTX Methotrexate, ALT Alanine Aminotransferase, AST Aspartate aminotransferase, ALP Alkaline phosphatase, ALB Albumin, TP Total protein. aSignificant different with control group at P < 0.05. bSignificant different with MTX at P < 0.05