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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Ethanol extract of propolis protects macrophages from oxidized low density lipoprotein-induced apoptosis by inhibiting CD36 expression and endoplasmic reticulum stress-C/EBP homologous protein pathway

Fig. 1

EEP reduces ox-LDL-induced intracellular lipid accumulation in RAW264.7 cells. a Cells were treated with ox-LDL (100 mg/L) in the absence or presence of EEP at different concentrations (7.5, 15 and 30 mg/L) for 24 h, and the intracellular lipid droplets were stained by oil red O. Representative lipid droplet staining images are shown. Scale bar = 20 μm. b The average integrated optical density (IOD) of lipid droplets stained with oil red O from differentiated macrophage-derived foam cells was calculated. c Under the same conditions as in (a), the intracellular total cholesterol (TC) content was measured using a tissue/cell TC assay kit. Data are expressed as the mean ± SEM of at least four independent experiments. **P < 0.01 versus vehicle-treated control; #P < 0.05, ##P < 0.01 versus ox-LDL treatment

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