Fig. 3

Histological appearance of scald wounds stained with hematoxylin and eosin [(a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), (l), (m), (n) and (o)]. The AJE-treated groups seemed to be better engaged in the wound repair processes (re-epithelialization, vascularization, inflammation, and development of granulation tissue). All treated groups showed sufficient vascularization. Significant masses of granulation tissue could be observed in the AJE-treated group on day 21 [(n), (o)]. Among them, the thickest granulation tissue was observed in 20 % AJE group on day 14 (j). Magnification: ×100. Abbreviations: CON, control; SSD, silver sulfadiazine; AJE, Ampelopsis japonica root ethanol extract; DM, dermis; ED, epidermis; HF, hair follicle; E, epithelialization; GT, granulation tissue; BC, blood capillaries; TME, tunica muscularis externa