Evaluation of analgesic, anti-inflammatory, anti-depressant and anti-coagulant properties of Lactuca sativa (CV. Grand Rapids) plant tissues and cell suspension in rats

Table 2 Edema volume in anti-inflammatory assay

Sr. No.	Treatment Groups (n = 5)	Dose	Edema volume (ml)^a ± S.D.
Sr. No.	Treatment Groups (n = 5)	Dose	1 h	2 h	3 h	4 h
Group-I	Negative control (saline)	1 ml/Kg	0.49 ± 0.02	0.6 ± 0.03	0.68 ± 0.02	1.15 ± 0.02
Group-II	Diclofenac potassium	10 mg/Kg	0.38 ± 0.01**	0.25 ± 0.02**	0.17 ± 0.01**	0.06 ± 0.01**
Group-III	Cell suspension exudate	1 ml/Kg	0.49 ± 0.04*	0.47 ± 0.05*	0.35 ± 0.05*	0.34 ± 0.05*
Group-IV	Leaf MC	1 g/Kg	0.48 ± 0.05*	0.49 ± 0.05*	0.38 ± 0.06**	0.33 ± 0.04**
Group-V	Seed MC	1 g/Kg	0.48 ± 0.08*	0.47 ± 0.08**	0.42 ± 0.06*	0.40 ± 0.07*
Group-VI	Leaf aqueous	1 g/Kg	0.48 ± 0.02*	0.42 ± 0.03*	0.28 ± 0.05*	0.26 ± 0.03*
Group-VII	Seed aqueous	1 g/Kg	0.47 ± 0.08*	0.44 ± 0.05*	0.42 ± 0.07*	0.39 ± 0.08*

Values are expressed in mean ± S.D. * p < 0.05, ** p < 0.01 statistically significant as compared to control group
^aDifference in initial paw volume and after carrageenan injection

ISSN: 2662-7671