Fig. 8

Beneficial effects of PMC-12 on the spatial memory function in MCAO mice. Morris water maze test was performed from 22 d to 25 d after MCAO. Administration of PMC-12 resulted in significantly improved memory function of MCAO mice during the late phase of the experiment. There was no significant differences in the results by two different doses (100 and 500 mg/kg) of PMC-12. Mean ± SEM. ^###P < 0.001 vs. control; ***P < 0.001 vs. MCAO mice (vehicle)