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Table 4 Effect of C. grevei MeOH extract on the activity of ALT, AST, ALP and LDH in serum and LDH in liver homogenate of mice exposed to cypermethrin

From: Antioxidant activity and hepatoprotective potential of Cedrelopsis grevei on cypermethrin induced oxidative stress and liver damage in male mice

Treatments

ALT

AST

ALP

LDH

(U/L)

(U/L)

(U/L)

Serum(U/L)

Liver(U/g tissue)

Control

44.36±0.92a

53.33±0.32a

89.88±1.77a

176.83±6.96a

158.30±11.83b

Ext 150

45.23±0.92a

52.82±0.24a

90.97±1.29a

172.87±8.38a

160.55±10.32b

Ext 300

43.84±1.02a

53.45±0.57a

88.99±1.80a

178.32±10.05a

161.90±8.98b

Cyp

60.62±1.43c

69.39±2.33c

131.45±3.32d

243.21±8.23c

114.23±4.86a

Cyp+ Ext 150

55.88±1.26b

63.88±1.32b

113.84±3.05c

222.61±8.95bc

115.04±4.91a

Cyp+ Ext 300

53.16±1.18b

60.70±2.23b

103.10±2.25b

203.32±7.88b

133.12±2.92a

  1. Each value is a mean of 6 animals ± S.E.; a, b, c, dvalues are not shared superscripts letters (a, b, c, d) differ significantly at P≤ 0.05; Con: control; Cyp: cypermethrin; Ext 150 & Ext 300; 150 and 300 mg/ kg b.wt of C. grevei MeOH extract. ALT: alanine aminotransferases; AST: aspartate aminotransferases; ALP: alkaline phosphatase; LDH: lactate dehydrogenase