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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Xia-yu-xue decoction (XYXD) reduces carbon tetrachloride (CCl4)-induced liver fibrosis through inhibition hepatic stellate cell activation by targeting NF-κB and TGF-β1 signaling pathways

Fig. 2

Effects of XYXD on HSC activation and Col production in CCl4-induced liver fibrosis in mice. a, liver sections were stained with α-SMA (×200, n = 3), Brown staining indicates immunopositivity. b, Expression of α-SMA was analyzed using real-time PCR analysis (n = 6). c, Expression of Col 1(α1) was analyzed using real-time PCR analysis (n = 6). d, Hyp content of liver tissue was measured. The number in Hyp and Sirius red detection was as the same as the animal number in each group. The data represented the mean ± SD *P < 0.05, * *P < 0.01, vs normal mice, #P < 0.05, ##P < 0.01, vs 6 wk

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