Skip to main content

Table 2 Oxidative stress markers, malondialdehyde (MDA) and nitric oxide (NO), and antioxidant enzyme activities in pancreatic tissues

From: Suppression of acute pancreatitis by L-lysine in mice

Group: I II III IV
Parameter (Normal) (Arginine, 400 mg/kg) (Arginine + Lysine) Treated (Arginine + Lysine) Protected
MDA (mmol/mg protein)     
Mean ± SD 48 ± 4.5 107 ± 13 81 ± 10 59 ± 5.1
P value --- <0.001 <0.01 <0.001
P*   --- <0.001 <0.001
NO (ug/mg protein)     
Mean ± SD 5.9 ± 0.9 19 ± 2.3 11.0 ± 2 9 ± 0.6
P value --- <0.001 <0.001 <0.001
P*   -- <0.001 <0.001
SOD (U/ mg protein)     
Mean ± SD 1225 ± 798 ± 96 869 ± 102 998 ± 152
P value 203 <0.001 <0.001 <0.001
P*    <0.001 <0.001
GPx (U/ mg protein)     
Mean ± SD 733 ± 56 1450 ± 101 1100 ± 92 980 ± 122
P value --- <0.05 <0.05 <0.001
P*   -- <0.05 <0.001
Reduced glutathione (ug/ mg     
protein) 222 ± 21 97 ± 11 133 ± 32 175 ± 35
Mean ± SD --- <0.05 <0.05 <0.01
P value   -- <0.05 <0.01
P*     
Catalase (U/ mg protein)     
Mean ± SD 96 ± 10.3 65 ± 7 63 ± 2.2 73 ± 2.5
P value --- <0.05 <0.01 <0.01
P*   -- <0.01 <0.01
  1. SOD, super oxide dismutase; GPx, glutathione peroxidase; P < 0.05 compared with the control
  2. * Treated versus untreated