Table 2 Oxidative stress markers, malondialdehyde (MDA) and nitric oxide (NO), and antioxidant enzyme activities in pancreatic tissues

MDA (mmol/mg protein)

Mean ± SD

48 ± 4.5

107 ± 13

81 ± 10

59 ± 5.1

P value

---

<0.001

<0.01

<0.001

P*

---

<0.001

<0.001

NO (ug/mg protein)

Mean ± SD

5.9 ± 0.9

19 ± 2.3

11.0 ± 2

9 ± 0.6

P value

---

<0.001

<0.001

<0.001

P*

--

<0.001

<0.001

SOD (U/ mg protein)

Mean ± SD

1225 ±

798 ± 96

869 ± 102

998 ± 152

P value

203

<0.001

<0.001

<0.001

P*

<0.001

<0.001

GPx (U/ mg protein)

Mean ± SD

733 ± 56

1450 ± 101

1100 ± 92

980 ± 122

P value

---

<0.05

<0.05

<0.001

P*

--

<0.05

<0.001

Reduced glutathione (ug/ mg

protein)

222 ± 21

97 ± 11

133 ± 32

175 ± 35

Mean ± SD

---

<0.05

<0.05

<0.01

P value

--

<0.05

<0.01

P*

Catalase (U/ mg protein)

Mean ± SD

96 ± 10.3

65 ± 7

63 ± 2.2

73 ± 2.5

P value

---

<0.05

<0.01

<0.01

P*

--

<0.01

<0.01