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Table 2 DRD2 TaqIA genotypic distribution and allelic frequencies

From: Association between the traditional Chinese medicine pathological factors of opioid addiction and DRD2/ANKK1 TaqIA polymorphisms

 

Genotypic Distribution (%)

Allele Frequency (%)

 

Group

A1A1

A1A2

A2A2

A1

A2

HWEP-value

Full (n = 502)

71 (14.1)

252 (50.2)

179 (35.7)

394 (39.2)

610 (60.8)

0.238

Males (n = 289)

39 (13.5)

137 (47.4)

113 (39.1)

215 (37.2)

363 (62.8)

 

Females (n = 213)

32 (15.0)

115 (54.0)

66 (31.0)

179 (42.0)

247 (58.0)

 

Opioid addicts (n = 347)

50 (14.4)

168 (48.4)

129 (37.2)

268 (38.6)

426 (61.4)

0.692

Health group (n = 155)

21 (13.5)

84 (54.2)

50 (32.3)

126 (40.6)

184 (59.4)

0.125

Addiction intensity = 1

26 (7.49)

88 (23.4)

58 (16.7)

140 (20.2)

204 (29.4)

 

Addiction intensity = 2

24 (6.91)

81 (23.3)

70 (20.2)

129 (18.6)

221 (31.8)

 
  1. Genotype comparison between males and females: χ2 = 3.53, df = 2, p = 0.171
  2. Genotype comparison between opioid addicts and health group: χ2 = 1.034, df = 2, p = 0.596
  3. Genotype comparison between different addiction intensities: χ2 = 1.469, df = 2, p = 0.480
  4. Full: includes both males and females
  5. Hardy-Weinberg equilibrium of genotype distributions of each polymorphism was tested for all of the participants, opioid addicts, and health group
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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