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Table 1 Plants used in the present study and evidence of their bioactivities

From: Antibacterial and antibiotic resistance modifying activity of the extracts from allanblackia gabonensis, combretum molle and gladiolus quartinianus against Gram-negative bacteria including multi-drug resistant phenotypes

Samples, family, and herbarium numbera Traditional treatment Area of plant collection Known bioactive or potentially active compounds Screened biological activities of the crude extracts and known bioactive compounds
Allanblackia gabonensis Pellegr. (Clusiaceae); 17275SRF/Cam Dysentery, cold, toothache [13]; pain, rheumatism, inflammations [14, 15]. Lebialem, South West region of Cameroon; (4°10′N 9°14′E/4.167°N 9.233°E) Not reported Crude extracts: Analgesic and anti-inlammatory effect of aqueous extract of the stem bark [14]; crude methanol fruits extracts (40 μg/mL) showed to inhibit growth of CCRF-CEM leukemia cells at about 50 % [16].
Gladiolus quartinianus A. Rich (Iridaceae); 17260/SRF/Cam Infections of the skin, gut, urogenital system, and upper respiratory tract [17], gonorrhea, infectious conditions, constipation and dysentery [18]. Lebialem, South-West region of Cameroon; (4°10′N 9°14′E/4.167°N 9.233°E) Not reported Methanol crude extract was reported to possess moderate to significant anticancer activity (IC50: 29.60 to10.57 μg/mL) against drug-resistance cancer cell lines [16]
Combretum molle R. Br. ex G. Don (Combretaceae); 33311/ HNC Fever, abdominal pains, convulsion, worm infections, human immunodeficiency virus (HIV)/acquiredimmune deficiency syndrome (AIDS) related infections [19]; hookworm, snake bite, leprosy, dysentery, general body swellings, arthritic and other inflammatory conditions, sterility, constipation [20, 21]; Parasitic, protozoan, infectious diseases [22], malaria [23] University of Dschang, West region of Cameroon; (6°30′N 10°30′E/6.500°N 10.500°E) Mollic acid glucoside [21]); β-D-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate,combregenin, arjungenin, arjunglucoside I, and combreglucoside [24] . Crude extracts were evaluated for: antibacterial activity [2527]; antimycobacterial [28]; antifungal effects [29]; antimalarial [30]; anthelmintic activities [31]; anti-HIV by inhibition of ribonuclease-H [19]; Cytotoxic effects against T-24 bladder cancer cells [32]; Anti-inflammatory activity [24]; in vitro anticholinesterase and inhibitory effects on Rabbit Breathing [33]. Compounds: mollic acid glucoside (MAG) showed analgesic, anti-inflammatory properties in mice and rats [21], cardiovascular effect [34]; hypoglycaemic effect [35]; Punicalgin and CM-A, two isolated tannins were assessed for their anti-HIV activity against human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) [36].
  1. aPlants were identified at the Cameroon National Herbarium (HNC)