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Table 1 Levels of independent variables for reflux extraction condition based on CCD

From: Optimization protocol for the extraction of 6-gingerol and 6-shogaol from Zingiber officinale var. rubrum Theilade and improving antioxidant and anticancer activity using response surface methodology

 

Coded

Variable

−1

0

1

Axial (−α)

Axial (+α)

X1: extraction temperature

50

65

80

47.1

82.8

X2: extraction time

2

3

4

1.8

4.1