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Table 1 Effect of Av-EtOH on carrageenan-induced hind paw edema in mice

From: Antinociceptive and anti-inflammatory activities of the ethanolic extract of Annona vepretorum Mart. (Annonaceae) in rodents

Drug treatments Dose (mg/kg) Paw volume (ml)
   1 h 2 h 3 h 4 h 5 h
Saline   0.09 ± 0.01 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00
Saline + Carr   0.47 ± 0.09 0.60 ± 0.12 0.37 ± 0.05 0.24 ± 0.04 0.19 ± 0.06
Av-EtOH 25 0.09 ± 0.05*** 0.25 ± 0.05** 0.36 ± 0.05 0.29 ± 0.07 0.20 ± 0.05
Av-EtOH 50 0.16 ± 0.06** 0.33 ± 0.06* 0.22 ± 0.06 0.31 ± 0.06 0.28 ± 0.07
Av-EtOH 100 0.12 ± 0.07*** 0.17 ± 0.09*** 0.22 ± 0.09 0.25 ± 0.09 0.17 ± 0.08
Indomethacin 20 0.06 ± 0.03*** 0.05 ± 0.02*** 0.03 ± 0.02*** 0.07 ± 0.03 0.03 ± 0.03
  1. *P < 0.05; **P < 0.01; ***P < 0.001. Carr: carrageenan