Gastroprotective and ulcer healing effects of piptadeniastrum Africanum on experimentally induced gastric ulcers in rats

Table 3 Effects of stem bark aqueous and methanol extracts of P. africanum on gastric ulcer induced by acetic acid

Treatment	Dose (mg/kg)	n	US (mm²)	Mucus weight (mg)	I %
Normal	/	6	0.00 ± 0.00**	107.00 ± 1.71*	/
Distilled water	/	6	94.07 ± 7.99	177.17 ± 7.67	/
Maalox	50	6	43.17 ± 1.05**	114.17 ± 1.14**	54.41
Ranitidine	50	6	12.56 ± 0.00**	109.00 ± 2.00**	86.73
Aqueous extract of P. africanum	125	6	37.95 ± 1.06**	130.17 ± 2.33**	59.92
	250	6	15.04 ± 0.84**	126.00 ± 1.48**	84.12
	500	6	38.21 ± 0.97**	134.50 ± 1.75**	59.65
Methanol extract P. africanum	125	6	28.00 ± 1.57**	151.17 ± 3.23**	70.43
	250	6	42.15 ± 1.10**	147.67 ± 9.63**	55.49
	500	6	40.16 ± 0.65**	139.33 ± 3.60**	57.59

n = number of animals per group, US = ulcer surface, I % = inhibition percentage
**Significant difference at 0,01 in relation to the control group having received distilled water

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