Skip to main content

Table 2 Effect of endophytic extracts (0.1 mg/mL) on the secretion of TNF-α in BV2 microglia cells1

From: Malaysian endophytic fungal extracts-induced anti-inflammation in Lipopolysaccharide-activated BV-2 microglia is associated with attenuation of NO production and, IL-6 and TNF-α expression

 

TNF-α production (pg/mL)

 

Unstimulated

Stimulated with LPS

 

24 h ± SEM

48 h ± SEM

24 h ± SEM

48 h ± SEM

BV2

33.84 ± 3.3

45.78 ± 13.5

4102.62 ± 999.7

2627.97 ± 432.3

HAB16R12

42.44 ± 21.7

61.80 ± 29.8

1150.71 ± 701.4*

1050.06 ± 577.7*

HAB16R13

43.33 ± 1.9

79.82 ± 2.7

960.88 ± 222.7*

982.20 ± 134.8*

HAB16R14

23.83 ± 4.6

58.51 ± 1.2

424.63 ± 98.0*

490.96 ± 86.7*

HAB16R18

32.22 ± 6.1

73.15 ± 0.9

1072.08 ± 332.7*

1052.11 ± 193.7*

HAB8R24

77.28 ± 6.4

103.56 ± 9.1

1511.54 ± 174.5*

1295.21 ± 265.6*

  1. 1Data are expressed as means ± SEM of three independent experiments. *P < 0.05, significantly different when compared to LPS-treated control (BV2)