Fig. 1

Liriope platyphylla extract (LPE) exerted neuroprotective effects against H₂O₂-induced cell loss in SH-SY5Y neuroblastoma cells. a SH-SY5Y cells were seeded in 96-well plates (5 × 10⁴ cells/ml) and cultured for 24 h. Cells were treated with the indicated concentrations of LPE for 24 h. LPE treatment at concentrations up to 50 μg/ml had no significant effect on SH-SY5Y cell viability. However, high LPE concentrations (100 – 500 μg/ml) decreased cell viability. The values shown are means  ±  standard errors (SE; n  =  8). *p < 0.05, **p < 0.01 compared to vehicle b Neuroprotective effect of LPE against H₂O₂-induced cytotoxicity in SH-SY5Y cells. Cells were pretreated with LPE for 6 h, and then co-treated with LPE and 100 μM H₂O₂ for 24 h. The values shown are means  ±  SE (n  =  8). **p < 0.01, compared to vehicle without H₂O₂, ^##p < 0.01, compared to vehicle with H₂O₂