Table 3 Effect of different extracts of Kaempferia galanga on open field test in mice
From: Study of sedative activity of different extracts of Kaempferia galanga in Swiss albino mice
Group | Dose (mg/kg) | Number of movements (% of Number of movements inhibition) | ||||
|---|---|---|---|---|---|---|
0 min | 30 min | 60 min | 90 min | 120 min | ||
Control | 5 ml/kg | 112.83 ± 6.24 | 112.5 ± 5.67 | 103.33 ± 11.39 | 99 ± 3.95 | 90.67 ± 1.52 |
Diazepam | 2 | 113 ± 2.62 | 57.83 ± 9.68* (48.59 %) | 46.67 ± 11.28* (54.83 %) | 37.83 ± 11.67** (61.78 %) | 26.67 ± 14.33** (70.58 %) |
ACR | 100 | 64.83 ± 17.24 | 25.17 ± 12.4** (77.62 %) | 18 ± 4.76** (82.58 %) | 23.67 ± 7.54** (76.09 %) | 27 ± 6.76** (70.22 %) |
200 | 91 ± 8.97 | 15.17 ± 4.73** (86.52 %) | 6.5 ± 2.38** (93.71 %) | 10.83 ± 3.58** (89.06 %) | 10.83 ± 3.98** (88.05 %) | |
PEF | 100 | 70.17 ± 11.86 | 14 ± 7.06** (87.55 %) | 12.17 ± 4.46** (88.22 %) | 11 ± 4.26** (88.88 %) | 17.33 ± 4.94** (80.88 %) |
200 | 86.67 ± 11.14 | 13.83 ± 7.89** (87.71 %) | 9.5 ± 1.38** (90.80 %) | 9 ± 3.03** (90.90 %) | 6.5 ± 3.04** (92.83 %) | |
CHF | 100 | 90 ± 7.19 | 31.5 ± 5.19** (72.00 %) | 24.33 ± 9.36** (76.45 %) | 25.83 ± 5.28** (73.90 %) | 15.33 ± 5.94** (83.09 %) |
200 | 104.83 ± 8.18 | 12 ± 4.84** (89.33 %) | 11.67 ± 6.51** (88.70 %) | 11.67 ± 6.02** (87.21 %) | 13.83 ± 6.99** (84.75 %) | |
MEF | 100 | 84.17 ± 12.54 | 32.67 ± 17.79* (70.96 %) | 21.33 ± 11.97** (79.36 %) | 13.17 ± 3.50** (86.69 %) | 10.83 ± 7.06** (88.05 %) |
200 | 90.83 ± 16.28 | 19.83 ± 7.66** (82.37 %) | 12 ± 3.71** (88.38 %) | 10.33 ± 3.67** (89.56 %) | 10.83 ± 3.98** (88.05 %) | |
ACL | 100 | 71.83 ± 22.56 | 44.83 ± 18.22* (60.15 %) | 26.83 ± 18.57** (74.03 %) | 11.33 ± 10.73** (88.55 %) | 6.33 ± 6.32** (93.01 %) |
200 | 79.67 ± 11.34 | 31 ± 11.12* (72.44 %) | 16.17 ± 3.49** (84.35 %) | 6 ± 0.77** (93.94 %) | 4 ± 1.26** (95.58 %) | |