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Table 1 Inhibition parameters (μg/ml) of the MeOH extract and compounds fromO. spinosaagainst microbial species

From: Antimicrobial and antioxidant flavonoids from the leaves of Oncoba spinosa Forssk. (Salicaceae)

Microorganisms Inhibition parameters MeOH extract 2 3 4 5 Reference drugs*
Enterobacter aerogenes ATCC13048 MIC 256 64 128 32 32 64
MBC 512 64 128 64 32 64
MBC/MIC 2 1 1 2 1 1
Escherichia coli ATCC8739 MIC 512 128 >256 128 64 64
MBC 1024 256 nd 128 64 64
MBC/MIC 2 2 nd 1 1 1
Klebsiella pneumoniae ATCC11296 MIC 256 64 256 32 8 16
MBC 512 64 256 64 16 16
MBC/MIC 2 1 1 2 2 1
Staphylococcus aureus MIC 1024 256 >256 128 64 64
MBC 1024 >256 nd 128 128 64
MBC/MIC 1 nd nd 1 2 1
Candida parapsilosis MIC 1024 64 64 128 >256 256
MFC >2048 64 128 256 nd 256
MFC/MIC nd 1 2 2 nd 1
Candida albicans ATCC 9002 MIC 2048 128 >256 256 >256 128
MFC >2048 128 nd 256 nd 128
MFC/MIC nd 1 nd 1 nd 1
Cryptococcus neoformans IP 90526 MIC 1024 64 128 128 >256 128
MFC >2048 64 128 128 nd 256
MFC/MIC nd 1 1 1 nd 2
  1. *: nystatin for fungi and chloramphenicol for bacteria; nd: not determined; MIC: Minimum Inhibitory Concentration; MBC: Minimum Bactericidal Concentration; MFC: Minimum Fungicidal Concentration.
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