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Table 5 Effect of AHM and its fraction in hot plate test

From: Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis

Group Dose/route Latency time in seconds
   0 min 30 min 60 min 120 min
Saline 10 ml, i.p. 9.83 ± 0.601 9.36 ± 0.317 9.3. ± 0.881 9.167 ± 0.44
AHM 50 mg/kg, p.o. 9.61 ± 0.1675 12.33 ± 0.881** 17.00 ± 0.577*** 18.33 ± 0.66***
100 mg/kg, p.o. 9.76 ± 0.145 17.0 ± 0.57*** 22.334 ± 1.201*** 24.0 ± 0.557***
150 mg/kg, p.o. 9.74 ± 0.52 20.66 ± 0.881*** 26.0 ± 0.577*** 26.33 ± 0.334***
AHE 50 mg/kg, p.o. 9.63 ± 0.185 13.0 ± 0.577*** 17.33 ± 0.667*** 19.33 ± 0.333***
100 mg/kg, p.o. 9.83 ± 0.167 17.66 ± 0.88*** 23.0 ± 0.577*** 24.33 ± 0.333***
150 mg/kg, p.o. 9.667 ± 0.166 22.0 ± 0.577*** 26.66 ± 0.33*** 27.0 ± 0.577***
Diclofenac sodium 10 mg/kg, i.p. 9.67 ± 0.667 21.66 ± 0.88*** 26.16 ± 0.89*** 26.66 ± 1.00***
Fluoxetine 10 mg/kg, i.p. 9.66 ± 0.881 15.33 ± 0.334*** 20.33 ± 0.90*** 21.33 ± 0.667***
  1. Data values shown represent mean ± SEM (n = 6). **p < 0.01, ***p < 0.001 versus saline treated group (Two-way ANOVA followed by Bonferroni multiple comparison test).