Skip to main content

Table 4 Effect of AHM and its fraction on acetic acid induced writhing

From: Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis

Groups

Drug (dose), route

No. of writhing (mean ± SEM)

% inhibition

Saline

10 ml/kg

70.38 ± 2.7

0

AHM

50 mg/kg,p.o.

27.65 ± 1.005***

60.71 ± 0.66

100 mg/kg, p.o.

18.09 ± 1.24***

74.29 ± 1.20

150 mg/kg, p.o.

16.15 ± 1.175***

77.05 ± 1.70

AHE

50 mg/kg,p.o.

18.25 ± 1.25***

74.06 ± 1.15

100 mg/kg, p.o.

15.00 ± 1.00***

78.68 ± 1.05

150 mg/kg, p.o.

12.75 ± 1.25***

81.88 ± 0.05

Diclofenac sodium

10 mg/kg, i.p.

13.22 ± 1.89***

81.65 ± 1.10

Aspirin

10 mg/kg, i.p.

20.13 ± 1.12***

71.39 ± 2.00

  1. Data values shown represent mean ± SEM (n = 6). ***p < 0.001 versus only acetic acid treated group (One-way ANOVA followed by Tukey’s Multiple Comparison Test).