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Table 4 Effect of AHM and its fraction on acetic acid induced writhing

From: Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis

Groups Drug (dose), route No. of writhing (mean ± SEM) % inhibition
Saline 10 ml/kg 70.38 ± 2.7 0
AHM 50 mg/kg,p.o. 27.65 ± 1.005*** 60.71 ± 0.66
100 mg/kg, p.o. 18.09 ± 1.24*** 74.29 ± 1.20
150 mg/kg, p.o. 16.15 ± 1.175*** 77.05 ± 1.70
AHE 50 mg/kg,p.o. 18.25 ± 1.25*** 74.06 ± 1.15
100 mg/kg, p.o. 15.00 ± 1.00*** 78.68 ± 1.05
150 mg/kg, p.o. 12.75 ± 1.25*** 81.88 ± 0.05
Diclofenac sodium 10 mg/kg, i.p. 13.22 ± 1.89*** 81.65 ± 1.10
Aspirin 10 mg/kg, i.p. 20.13 ± 1.12*** 71.39 ± 2.00
  1. Data values shown represent mean ± SEM (n = 6). ***p < 0.001 versus only acetic acid treated group (One-way ANOVA followed by Tukey’s Multiple Comparison Test).