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Table 3 Effect of AHM and its fraction on prostaglandin E 2 -induced paw edema in rats

From: Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis

Treatment Dose/route Percent inhibition of edema Volume
+1 h +2 h +3 h +4 h
AHM 50 mg/kg, p.o. 2.44 ± 0.29 18.58 ± 1.744*** 52.25 ± 1.52*** 54.186 ± 3.13***
100 mg/kg, p.o. 3.76 ± 0.176 33.31 ± 1.084*** 72.86 ± 2.081*** 75.19 ± 2.62***
150 mg/kg, p.o. 4.16 ± 0.176 42.50 ± 1.76*** 86.72 ± 3.45*** 86.11 ± 1.41***
AHE 50 mg/kg, p.o. 4.72 ± 0.355 24.16 ± 1.20*** 64.34 ± 1.88*** 75.68 ± 2.61***
100 mg/kg, p.o. 4.33 ± 0.12 37.77 ± 1.36*** 77.21 ± 2.23*** 84.12 ± 0.90***
150 mg/kg, p.o. 4.80 ± 0.152 59.338 ± 3.05*** 90.57 ± 0.76*** 91.345 ± 0.57***
Diclofenac sodium 10 mg/kg, i.p. 5.13 ± 0.145 55.83 ± 2.63*** 87.72 ± 2.53*** 88.11 ± 0.68***
  1. Data values shown represent mean ± SEM (n = 6). ***p < 0.001 versus only PGE2 treated group (Two-way ANOVA followed by Bonferroni multiple comparison test).
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