Skip to main content

Advertisement

Table 1 Trial process chart

From: A protocol of histone modification-based mechanistic study of acupuncture in patients with stable angina pectoris

  Baseline Treatment phase Follow-up phase
  −1 week 0 day 4 weeks 8 weeks 12 weeks 16 weeks
Patients       
Inclusion and exclusion *      
Allocate informed consent *      
Sign the informed consent   *     
Medical history *      
Laboratory test *      
Randomization   *     
Intervention       
PC6 group (n = 20)   12 sessions of acupuncture    
Non-acupoint point group (n = 20)     
Comparison       
Control group (n = 20)       
Outcomes       
Angina attacks in four weeks    * * * *
VAS   * * * * *
Dosage of nitroglycerin   * * * * *
6-MWT   * *    
SAQ   * * *   
SAS   * * *   
SDS   * * *   
The incidence of cardiovascular episode during the 4 months       *
Dynamic ECG Observation of the changes of ST-T   * *    
Clinic evaluation       
Safety of electro-acupuncture    *    *
Adverse events    * * * *
Patient’s compliance    *    
Reasons of drop-out withdrawals    *    
Laboratory evaluation       
Blood collection   * *    *
RNA & DNA extraction   * *    *
RNA-Seq & ChIP-Seq data analysis    *    *