Table 1 Trial process chart

Patients

Inclusion and exclusion

*

Allocate informed consent

*

Sign the informed consent

*

Medical history

*

Laboratory test

*

Randomization

*

Intervention

PC6 group (n = 20)

Non-acupoint point group (n = 20)

Comparison

Control group (n = 20)

Outcomes

Angina attacks in four weeks

*

*

*

*

VAS

*

*

*

*

*

Dosage of nitroglycerin

*

*

*

*

*

6-MWT

*

*

SAQ

*

*

*

SAS

*

*

*

SDS

*

*

*

The incidence of cardiovascular episode during the 4 months

*

Dynamic ECG Observation of the changes of ST-T

*

*

Clinic evaluation

Safety of electro-acupuncture

*

*

Adverse events

*

*

*

*

Patient’s compliance

*

Reasons of drop-out withdrawals

*

Laboratory evaluation

Blood collection

*

*

*

RNA & DNA extraction

*

*

*

RNA-Seq & ChIP-Seq data analysis

*

*