Effect of F. mume on MBP expression in the white matter and the hippocampus.. Immunohistological staining was performed to evaluate the expression level of MBP in the white matter regions and the hippocampus in the sham-operated group (n = 8), the BCCAo + Vehicle group (n = 9), and the BCCAo + F. mume group (n = 9). (A) Representative photomicrograph of MBP-positive cells. (B) MBP level was decreased in the medial septum, the corpus callosum, the fimbria of the white matter, and the hippocampus of BCCAo-injured rats compared to sham-operated rats (*). Data were analyzed via ANOVA followed by the Tukey test.*, p < 0.05 versus the BCCAo + Vehicle group. LV, lateral ventricle; MS, medial septum; CC, corpus callosum; FI, fimbria; HC, hippocampus; CC, corpus callosum.