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Table 2 Effect of MPE and VTE on deep granulation tissue dry weight, protein, hydroxyproline (HXPR), hexosamine (HXAM) and hexuronic acid (HXUA): dead space wound study

From: Mallotus philippinensis Muell. Arg fruit glandular hairs extract promotes wound healing on different wound model in rats

Oral treatment (mg/kg, od × 10 days)

Dry tissue (mg/100 g bw)

Protein (mg/g dry tissue)

Connective tissue parameters

μg/mg protein

HXPR

HXAM

HXUA

Control (1%CMC)

72.2 ± 2.78

178.9 ± 12.8

157.8 ± 8.19

79.9 ± 8.22

18.9 ± 2.29

(100.0 ± 3.85)

(100.0 ± 7.15)

(100.0 ± 5.19)

(100.0 ± 10.3)

(100.0 ± 12.1)

MPE 200

83.7 ± 2.51a

230.8 ± 14.4a

220.1 ± 12.5b

133.7 ± 13.1b

27.2 ± 1.47a

(115.9 ± 3.48)

(129.0 ± 8.05)

(139.5 ± 7.92)

(167.3 ± 16.4)

(143.9 ± 7.78)

VTE 200

86.6 ± 2.76b

232.7 ± 11.4a

212.7 ± 9.40b

129.1 ± 9.37b

35.0 ± 2.00c

(119.9 ± 3.82)

(130.1 ± 6.37)

(134.8 ± 5.96)

(161.6 ± 11.7)

(185.2 ± 10.6)

  1. Results are mean ± SEM (n=6). Values in parenthesis indicate percent of respective control value.
  2. P values: a< 0.05, b< 0.01 and c< 0.001 compared to respective control group (Statistical analysis was done by one way analysis of variance followed by Dunnett’s test for multiple comparisons).