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Table 1 Effect of MPE and VTE on wound contraction, epithelization period and scar area in rats: excision wound study

From: Mallotus philippinensis Muell. Arg fruit glandular hairs extract promotes wound healing on different wound model in rats

Oral treatment (mg/kg, od)

Wound area in mm2/rat

  

Before treatment 0 day

After treatment

Fvalues*

Pvalues*

4thday

8thday

12thday

144hday

16thday

18thday

20thday

22ndday

  

Control (CMC)

531.2±7.9

432.8±8.9

308.1±15.1

201.3±11.4

125.2±9.1

91.7±4.8

44.7±2.4

18.7±2.4

5.5±0.3

486.4

0.000

(100.0±0.0)

(74.3±2.4)

(51.2±2.6)

(31.7±2.1)

(19.8±0.9)

(14.4±1.3)

(6.6±0.5)

(2.0±0.5)

(0.7±0.1)

MPE (200)

521.7±7.7

321.5±4.6c

198.5±6.6c

114.5±6.7c

83.7±4.2c

44.2±3.6c

20.8±1.4c

4.2±0.3c

0.0±0.0c

1692.0

0.000

(100.0±0.0)

(59.9±0.9)

(35.0±1.0)

(18.4±1.2)

(13.9±0.7)

(5.7±0.7)

(3.3±0.3)

(0.6±0.1)

(0.0±0.0)

VTE (200)

543.7±9.6

314.0±8.2c

187.8±10.9c

103.3±3.9c

43.3±5.9c

35.3±3.1c

6.7±0.6c

0.7±0.1c

0.0±0.0c

926.0

0.000

(100.0±0.0)

(53.5±1.5)

(25.5±2.1)

(17.4±0.8)

(5.2±1.2)

(4.6±0.6)

(0.9±0.1)

(0.1±0.02)

(0.0±0.0)

  1. Values are mean ± SEM (n= 6). Values in parenthesis indicate mean ± SEM percent of respective 0 day value using repeated measure ANOVA.
  2. Statistical analysis was done by repeated measure ANOVA* in between the group as indicated by P and F values in the table while, one way analysis of variance for multiple comparisons was applied between groups (Pc< 0.001 compared to respective day control group).