Oridonin alters the expression profiles of MicroRNAs in BxPC-3 human pancreatic cancer cells

Gui, Zhifang; Li, Shuquan; Liu, Xing; Xu, Bin; Xu, Jian

doi:10.1186/s12906-015-0640-5

Table 1 miRNA regulation of oridonin in BxPC-3 cells

From: Oridonin alters the expression profiles of MicroRNAs in BxPC-3 human pancreatic cancer cells

Reporter name^a	Log2-value^b	p-Value	Reporter name^a	Log2-value^b	p-Value^b
hsa-miR-513a-5p	15.70	2.09E-66	hsa-miR-27b-5p	−16.93	0.00E + 00
hsa-miR-3661	12.73	0.00E + 00	hsa-miR-205-3p	−16.63	0.00E + 00
hsa-miR-4470	12.24	0.00E + 00	hsa-miR-4262	−16.47	0.00E + 00
hsa-miR-409-3p	10.68	0.00E + 00	hsa-miR-499a-5p	−16.36	0.00E + 00
hsa-miR-3197	10.32	0.00E + 00	hsa-miR-3934-3p	−16.32	0.00E + 00
hsa-miR-5096	10.29	0.00E + 00	hsa-miR-193b-3p	−7.45	0.00E + 00
hsa-miR-4267	10.13	0.00E + 00	hsa-miR-421	−6.93	0.00E + 00
hsa-miR-466	8.90	0.00E + 00	hsa-miR-10b-3p	−5.74	0.00E + 00
hsa-miR-615-5p	8.80	0.00E + 00	hsa-miR-7641	−5.53	0.00E + 00
hsa-miR-7108-5p	8.13	0.00E + 00	hsa-miR-425-5p	−4.77	0.00E + 00
hsa-miR-6791-5p	7.92	0.00E + 00	hsa-miR-125b-5p	−4.38	0.00E + 00
hsa-miR-1246	6.86	0.00E + 00	hsa-miR-200b-3p	−3.98	0.00E + 00
hsa-miR-6807-5p	6.57	1.38E-43	hsa-miR-3960	−3.95	0.00E + 00
hsa-let-7f-5p	6.41	0.00E + 00	hsa-miR-132-3p	−3.55	0.00E + 00
hsa-miR-1307-3p	5.81	0.00E + 00	hsa-miR-361-5p	−3.34	0.00E + 00
hsa-miR-4514	5.36	1.44E-59	hsa-miR-3178	−3.31	0.00E + 00
hsa-miR-4472	5.22	0.00E + 00	hsa-miR-454-3p	−3.13	0.00E + 00
hsa-miR-6126	5.04	0.00E + 00	hsa-miR-320b	−2.71	0.00E + 00
hsa-miR-6073	4.60	1.24E-43	hsa-miR-455-3p	−2.62	0.00E + 00
hsa-miR-4301	4.26	0.00E + 00	hsa-miR-320e	−2.56	0.00E + 00
hsa-miR-4484	3.79	3.65E-71	hsa-miR-185-5p	−2.47	0.00E + 00
hsa-miR-30c-1-3p	3.65	0.00E + 00	hsa-miR-320c	−2.38	0.00E + 00
hsa-miR-4447	3.59	2.47E-42	hsa-miR-4521	−2.13	0.00E + 00
hsa-miR-7977	3.56	0.00E + 00	hsa-miR-320a	−2.10	0.00E + 00
hsa-miR-5787	3.47	2.93E-51	hsa-miR-193a-3p	−2.09	0.00E + 00
hsa-miR-7150	3.44	2.24E-47	hsa-miR-320d	−2.04	0.00E + 00
hsa-miR-4516	3.16	0.00E + 00	hsa-miR-92b-3p	−1.84	0.00E + 00
hsa-miR-1273 g-3p	3.06	0.00E + 00	hsa-let-7i-5p	−1.81	0.00E + 00
hsa-miR-6090	3.00	0.00E + 00	hsa-miR-183-5p	−1.79	0.00E + 00
hsa-miR-494-3p	2.98	1.06E-72	hsa-miR-365a-3p	−1.59	0.00E + 00
hsa-miR-6786-5p	2.87	1.26E-23	hsa-miR-186-5p	−1.54	0.00E + 00
hsa-miR-6727-5p	2.81	0.00E + 00	hsa-miR-125a-5p	−1.54	0.00E + 00
hsa-miR-98-5p	2.65	0.00E + 00	hsa-miR-151a-3p	−1.43	0.00E + 00
hsa-miR-668-3p	2.64	6.84E-65	hsa-miR-224-5p	−1.42	0.00E + 00
hsa-miR-1275	2.59	1.69E-50	hsa-miR-107	−1.40	0.00E + 00
hsa-miR-6125	2.53	1.03E-49	hsa-miR-93-5p	−1.34	0.00E + 00
hsa-miR-6087	2.50	0.00E + 00	hsa-miR-3609	−1.31	0.00E + 00
hsa-miR-4505	2.31	1.03E-10	sa-miR-103a-3p	−1.28	0.00E + 00
ha-smiR-7110-5p	2.26	3.03E-12	hsa-miR-4286	−1.22	0.00E + 00
hsa-miR-1260a	2.14	1.31E-09	hsa-miR-3607-5p	−1.20	0.00E + 00
hsa-miR-6803-5p	2.13	1.94E-10	hsa-miR-92a-3p	−1.19	0.00E + 00
hsa-miR-29c-3p	2.08	2.01E-13	hsa-miR-429	−1.17	0.00E + 00
hsa-miR-4466	2.04	3.57E-06	hsa-miR-20a-5p	−1.15	0.00E + 00
hsa-miR-1973	1.93	7.49E-09	hsa-miR-424-5p	−1.13	0.00E + 00
hsa-miR-4739	1.86	1.47E-04	hsa-miR-17-5p	−1.09	0.00E + 00
hsa-miR-3196	1.85	1.80E-15	hsa-miR-203a	−1.05	0.00E + 00
hsa-miR-4497	1.76	1.16E-13	hsa-miR-574-3p	−1.04	0.00E + 00
hsa-miR-378 g	1.76	2.93E-03	hsa-miR-378c	−1.03	0.00E + 00
hsa-miR-4459	1.73	5.05E-03	hsa-miR-423-5p	−1.01	0.00E + 00
hsa-miR-3665	1.70	2.46E-11
hsa-miR-638	1.64	2.41E-04
hsa-miR-7704	1.63	4.06E-08
hsa-let-7 g-5p	1.54	1.18E-05
hsa-let-7e-5p	1.52	3.00E-07
hsa-miR-4508	1.04	2.30E-08
hsa-miR-6089	1.03	2.17E-19
Reporter name ^c	Log2-value ^b	p-Value	Reporter name ^c	Log2-value ^b	p-Value
hsa-miR-328-5p	2.96	3.36E-18	hsa-miR-3943	−16.15	0.00E + 00
hsa-miR-5194	6.18	8.69E-39	hsa-miR-4536-3p	−16.08	0.00E + 00
hsa-miR-6085	2.55	2.40E-12	hsa-miR-1180-3p	−15.86	0.00E + 00
hsa-miR-6880-5p	2.69	1.08E-13	hsa-miR-3188	−15.82	0.00E + 00
hsa-miR-4791	14.87	2.29E-39	hsa-miR-1179	−15.81	0.00E + 00
hsa-miR-6124	3.00	1.28E-16	hsa-miR-3169	−9.50	0.00E + 00
hsa-miR-1233-5p	3.54	1.32E-20	hsa-miR-15b-3p	−7.42	0.00E + 00
hsa-miR-765	2.56	9.53E-10	hsa-miR-301a-3p	−6.71	0.00E + 00
hsa-miR-4463	2.34	1.77E-07	hsa-miR-101-3p	−6.63	0.00E + 00
			hsa-miR-3065-5p	−6.07	0.00E + 00
			hsa-miR-625-5p	−3.97	0.00E + 00
			hsa-miR-24-2-5p	−3.06	0.00E + 00
			hsa-miR-128-3p	−2.86	0.00E + 00
			hsa-miR-4289	−2.65	0.00E + 00
			hsa-miR-155-5p	−2.35	0.00E + 00
			hsa-miR-197-3p	−2.21	0.00E + 00
			hsa-miR-10a-5p	−2.08	0.00E + 00

^aTranscripts showing strong signals (signal ≥ 500; |Log2-value| ≥ 1).
^bOridonin/control.
^cTranscripts showing weak signals (350 < signal < 500; |Log2-value| ≥ 2).

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