SCRT inhibits cell viability and induces morphological changes in A549 cells. (A, B and C) A549 and WI-38 cells were treated with various concentrations of SCRT for the indicated times. The cell viability was measured by the trypan blue exclusion method (A) and the metabolic-dye-based MTT assay (B and C). Each point represents the mean ± SD of three independent experiments. The significance was determined by the Student’s t-test (*p < 0.05 vs. untreated control). (D) Cells were treated with the indicated concentrations of SCRT for 72 h and photographed under an inverted microscope (original magnification 200x).