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Table 4 Effect of methanol extract of M. malabathricum leaves (MEMM), quercitrin and ranitidine on levels of glutathione peroxidase (GTP), glutathione reductsase (GTR) and thiobarbituric acid reactive substances (TBARS) in rats of ethanol-induced gastric tissues

From: Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves

Experimental groups GTP (nmol min−1 mg of protein−1) GTR (nmol min−1 mg of protein−1) TBARS (nmol TBARS−1 mg of protein1)
Normal (Untreated) 316.22 ± 52.77 28.37 ± 0.91 2.81 ± 0.23
Negative Control (Ethanol) 127.83 ± 20.84* 12.74 ± 0.77* 6.27 ± 0.56*
100 mg/kg Ranitidine + Ethanol 186.81 ± 26.73# 14.39 ± 1.96 4.13 ± 1.07#
250 mg/kg MEMM + Ethanol 271.56 ± 41.31# 15.62 ± 1.01# 4.29 ± 0.33#
500 mg/kg MEMM + Ethanol 310.18 ± 30.07# 18.86 ± 2.34# 3.01 ± 0.92#
50 mg/kg Qurcitrin + Ethanol 201.16 ± 13.45# 17.33 ± 0.84# 3.17 ± 0.12#
250 mg/kg Qurcitrin + Ethanol 308.24 ± 22.87# 25.76 ± 1.41# 2.25 ± 0.33#
  1. The results were expressed as mean ± SEM.
  2. *significant at p < 0.05 when compared against the normal (untreated) group using the Student’s t-test.
  3. #significant at p < 0.05 when compared against the negative control (ethanol-treated) group using the ANOVA followed by Dunnett’s test.