Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves

Table 3 Effect of methanol extract of M. malabathricum leaves (MEMM), quercitrin and ranitidine on levels of superoxide dismutase (SOD), catalase (CAT) and myeloperoxidase (MPO) enzymes in rats of ethanol-induced gastric tissues

Experimental groups	SOD (mmol/min/mg of protein⁻¹)	CAT (mmol/min/mg protein⁻¹)	MPO (UI mg of protein⁻¹)
Normal (Untreated)	53.26 ± 2.93	5.04 ± 0.87	1.76 ± 0.28
Negative Control (Ethanol)	38.73 ± 4.81*	7.17 ± 0.72*	3.52 ± 0.23*
100 mg/kg Ranitidine + Ethanol	58.72 ± 5.80^#	5.11 ± 0.74^#	2.23 ± 0.18^#
250 mg/kg MEMM + Ethanol	42.38 ± 3.25	6.08 ± 0.59	2.88 ± 0.45^#
500 mg/kg MEMM + Ethanol	50.31 ± 6.06^#	5.32 ± 0.31^#	2.11 ± 0.28^#
50 mg/kg Qurcitrin + Ethanol	55.83 ± 4.22^#	5.18 ± 1.01^#	1.94 ± 0.63^#
250 mg/kg Qurcitrin + Ethanol	52.89 ± 5.09^#	5.41 ± 0.83^#	1.61 ± 0.19^#

*significant at p < 0.05 when compared against the normal (untreated) group using the Student’s t-test.
^#significant at p < 0.05 when compared against the negative control (ethanol-treated) group using the ANOVA followed by Dunnett’s test.

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