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Table 3 Effect of methanol extract of M. malabathricum leaves (MEMM), quercitrin and ranitidine on levels of superoxide dismutase (SOD), catalase (CAT) and myeloperoxidase (MPO) enzymes in rats of ethanol-induced gastric tissues

From: Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves

Experimental groups SOD (mmol/min/mg of protein−1) CAT (mmol/min/mg protein−1) MPO (UI mg of protein−1)
Normal (Untreated) 53.26 ± 2.93 5.04 ± 0.87 1.76 ± 0.28
Negative Control (Ethanol) 38.73 ± 4.81* 7.17 ± 0.72* 3.52 ± 0.23*
100 mg/kg Ranitidine + Ethanol 58.72 ± 5.80# 5.11 ± 0.74# 2.23 ± 0.18#
250 mg/kg MEMM + Ethanol 42.38 ± 3.25 6.08 ± 0.59 2.88 ± 0.45#
500 mg/kg MEMM + Ethanol 50.31 ± 6.06# 5.32 ± 0.31# 2.11 ± 0.28#
50 mg/kg Qurcitrin + Ethanol 55.83 ± 4.22# 5.18 ± 1.01# 1.94 ± 0.63#
250 mg/kg Qurcitrin + Ethanol 52.89 ± 5.09# 5.41 ± 0.83# 1.61 ± 0.19#
  1. *significant at p < 0.05 when compared against the normal (untreated) group using the Student’s t-test.
  2. #significant at p < 0.05 when compared against the negative control (ethanol-treated) group using the ANOVA followed by Dunnett’s test.
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