Table 2 Effect of bitter melon (ucche) on biochemical parameter in plasma and liver

AST(U/L)

19.0 ± 1.6

21.32 ± 1.68

37.9 ± 3.1

23.3 ± 4.0

0.0374

0.0012

0.0062

ALT(U/L)

13.8 ± 1.7

16.59 ± 2.62

30.5 ± 3.1

18.7 ± 1.9

0.0831

0.0012

0.0082

ALP(U/L)

50.8 ± 3.3

50.92 ± 2.76

81.2 ± 6.1

63.9 ± 4.7

0.0731

0.0001

0.0690

MDA(nmol/mL)

6.34 ± 0.37

3.57 ± 0.54

7.7 ± 0.91

6.71 ± 0.77

0.0731

0.0001

0.0690

NO (nmol/mL)

3.22 ± 0.27

2.24 ± 0.22

5.8 ± 0.3

1.15 ± 0.32

<0.0001

0.0195

<0.0001

APOP (nmol/mL equivalent to Chloramine-T)

82.60 ± 8.49

67.0 ± 9.2

164.4 ± 15.15

84.3 ± 8.8

0.0340

0.0102

0.3072

Catalase (U/min)

6.00 ± 0.32

4.28 ± 0.38

2.93 ± 0.60

5.07 ± 0.74

0.6960

0.0343

0.0011

GSH (ng/mg protein)

20.05 ± 1.81

18.39 ± 1.03

12.72 ± 0.57

16.39 ± 0.57

0.3788

0.0005

0.0270

AST(U/L)

36.18 ± 3.22

31.01 ± 3.46

65.18 ± 3.87

46.51 ± 2.11

0.0023

<0.0001

0.0594

ALT(U/L)

26.00 ± 3.88

34.67 ± 2.24

77.61 ± 4.80

28.77 ± 1.49

<0.0001

<0.0001

<0.0001

ALP(U/L)

30.33 ± 3.67

31.42 ± 3.54

113.53 ± 3.71

68.25 ± 3.67

<0.0001

<0.0001

<0.0001

NO (nmol/mL)

15.87 ± 1.56

20.21 ± 0.45

35.62 ± 4.21

18.11 ± 2.17

0.0225

0.0036

0.0006

MDA (nmol/mL)

21.85 ± 1.86

24.62 ± 4.88

57.16 ± 6.44

36.92 ± 1.98

0.0741

<0.0001

0.0226

APOP (nmol/mL equivalent to Chloramine-T)

365.00 ± 40.19

450.0 ± 75.83

1357.62 ± 91.06

977.50 ± 63.05

0.0491

< 0.0001

0.0097

Catalase (U/min)

52.13 ± 4.02

68.40 ± 5.92

26.32 ± 3.82

50.27 ± 2.33

0.0003

< 0.0001

0.3967

GSH (ng/mg protein)

21.22 ± 1.91

19.22 ± 1.13

45.98 ± 5.05

32.89 ± 1.79

0.0171

< 0.0001

0.0703