Psychopharmacological activity was determined by open field test using (A) total ambulation (B) central ambulation (C) standing up behaviour (D) emotional defecation parameters in mice. (p < 0.05). The active principles of serpentine (structure shown, B) of Rauvolfia serpentina (L.), total xanthones (structure shown, C) of Canscora decussata (Roxb.) Schult., cannabidiol (structure shown, D) of Cannabis sativa Linn. may be the reason for such effect.