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Table 3 Effect of YCHT on bile acids (BAs) and free fatty acids (FFAs) metabolism

From: Chlorpromazine-induced perturbations of bile acids and free fatty acids in cholestatic liver injury prevented by the Chinese herbal compound Yin-Chen-Hao-Tang

Compound Control Model YCHT
CA 10959.98 ± 3777.06 21454.91 ± 3738.66 10936.3 ± 1774.1
α-MCA 175.72 ± 4.15 3171.48 ± 690.76*** 1092.45 ± 188.1##
β-MCA 218.17 ± 5.07 2222.1 ± 771.15** 1754.07 ± 333.24
ω-MCA 231.65 ± 5.85 388.25 ± 90.3 331.23 ± 84.9
CDCA 832.91 ± 157.56 4203.03 ± 796.24** 3348.31 ± 377.81
DCA 1979.46 ± 262.43 3166.18 ± 144.98*** 383.96 ± 54.89###
LCA 24.46 ± 2.48 14.07 ± 1.19* 21.44 ± 4.16
UDCA 65.251 ± 15.73 262.81 ± 47.24** 173.88 ± 25.20
HDCA 6679.97 ± 598.89 3464.91 ± 463.26** 3997.04 ± 564.22
TCA 192.81 ± 25.91 621.46 ± 85.46*** 244.33 ± 34.33##
TCDCA 54.39 ± 7.79 244.88 ± 5.17*** 110.19 ± 17.09##
TDCA 299.94 ± 29.46 91.63 ± 13.68*** 115.99 ± 39.34
TLCA 12.03 ± 1.45 7.53 ± 0.49** 5.81 ± 0.24
TUDCA 11.12 ± 0.34 5.94 ± 0.70*** 7.55 ± 0.80
THDCA 757.34 ± 112.71 180.02 ± 19.41*** 192.5 ± 28.36
GCA 364.43 ± 72.98 1449.35 ± 89.25*** 466.99 ± 110.79 ###
GCDCA 47.42 ± 12.70 458.01 ± 49.91*** 122.86 ± 12.03###
GDCA 644.59 ± 147.35 21.98 ± 3.8*** 196.62 ± 36.89
GLCA 17.93 ± 1.56 13.55 ± 0.76** 13.62 ± 0.71
C 12:0 2.81 ± 0.021 2.60 ± 0.048 2.47 ± 0.03
C 14:0 2.78 ± 0.12 2.64 ± 0.08 2.23 ± 0.08
C 16:0 54.81 ± 2.12 59.43 ± 2.83 42.74 ± 2.8
C16:1n7 1.77 ± 0.05 1.88 ± 0.08 1.53 ± 0.06
C18:0 35.84 ± 1.47 37.49 ± 2.41 29.23 ± 2.33
C18:1n9 5.867 ± 0.11 8.58 ± 0.75** 4.30 ± 0.34###
C18:1n7 1.90 ± 0.89 2.01 ± 1.68 1.75 ± 0.73
C18;2n6 12.29 ± 0.3 18.2 ± 0.04** 8.69 ± 0.03###
C18:3n3 1.45 ± 0.03 1.546 ± 0.03 1.29 ± 0.03
C20:0 1.56 ± 0.05 1.532 ± 0.03 1.45 ± 0.01
C20:3n6 1.48 ± 0.03 1.65 ± 0.03** 1.53 ± 0.01#
C20:4n6 10.60 ± 0.50 14.74 ± 0.61*** 10.92 ± 0.77###
C20:5n3 2.33 ± 0.05 2.58 ± 0.16* 2.08 ± 0.03###
C22:6n3 4.91 ± 0.21 7.73 ± 0.67*** 4.95 ± 0.37###
  1. The results are expressed in ng/mL as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, significantly different from control group. #p < 0.05, ##p < 0.01, ###p < 0.001, significantly different from model group.