TY - JOUR AU - Yang, Qiaoling AU - Yang, Fan AU - Tang, Xiaowen AU - Ding, Lili AU - Xu, Ying AU - Xiong, Yinhua AU - Wang, Zhengtao AU - Yang, Li PY - 2015 DA - 2015/04/16 TI - Chlorpromazine-induced perturbations of bile acids and free fatty acids in cholestatic liver injury prevented by the Chinese herbal compound Yin-Chen-Hao-Tang JO - BMC Complementary and Alternative Medicine SP - 122 VL - 15 IS - 1 AB - Yin-Chen-Hao-Tang (YCHT), a commonly used as a traditional chinese medicine for liver disease. Several studies indicated that YCHT may improving hepatic triglyceride metabolism and anti-apoptotic response as well as decreasing oxidative stress .However, little is known about the role of YCHT in chlorpromazine (CPZ) –induced chlolestatic liver injury. Therefore, we aimed to facilitate the understanding of the pathogenesis of cholestatic liver injury and evaluate the effect of Yin-Chen-Hao-Tang (YCHT) on chlorpromazine (CPZ)-induced cholestatic liver injury in rats based on the change of bile acids (BAs) and free fatty acids (FFAs) alone with the biochemical indicators and histological examination. SN - 1472-6882 UR - https://doi.org/10.1186/s12906-015-0627-2 DO - 10.1186/s12906-015-0627-2 ID - Yang2015 ER -