Hepatic mRNA expressions of cholesterol metabolism-related genes. Hepatic cholesterol 7 alpha-hydroxylase (CYP7A1) (A), LDL receptor (B), and HMG-CoA reductase (C) in male rats, fed with SP-diet and HFC-diet with red yeast rice extract and rosuvastatin for 30 days. Values were normalized to reference gene GAPDH, and are expressed relative to the control level (SP-control). Data are expressed as mean ± standard deviation (SD) (n = 8). Each value is the mean ± SD (n = 8). Values with different superscript letters (a,b,c) in the each column differ significantly (p < 0.05) by the Tukey HSD test.