Figure 6From: Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathwayQYGS suppresses Ang II-induced up-regulation of NOX4, p22phox, and GTP-Rac1 in NOX4 siRNA-transfected HMCs. RT-PCR (A) and Western blot analysis (B) results of the effects of QYGS on NOX4, p22phox, and GTP-Rac1 upon transfection with non-targeting siRNA or NOX4 siRNA. Data are presented as means ± SEM (n = 3). **P < 0.01 as compared with the RNAcon group. #P < 0.05, ##P < 0.01 as compared with the vehicle group. $P < 0.05, $$P < 0.01 as compared with the Ang II model group.Back to article page