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Table 2 Association of FTO rs7193144 (T > C) with determination of constitutional type

From: The obesity-risk variant of FTO is inversely related with the So-Eum constitutional type: genome-wide association and replication analyses

Population SE versus NSE TE versus NTE SY versus NSY
MAF (n)    MAF (n)    MAF (n)   
SE NSE OR (95% CI) P TE NTE OR (95% CI) P SY NSY OR (95% CI) P
Stage 1 0.106 (1903) 0.140 (1903) 0.714 (0.620, 0.823) 3.07E-06 0.135 (1903) 0.114 (1903) 1.224 (1.067, 1.405) 0.00395 0.122 (1902) 0.131 (1903) 0.918 (0.801, 1.053) 0.222
Stage 2 0.122 (833) 0.146 (835) 0.764 (0.616, 0.945) 0.0135 0.146 (837) 0.119 (831) 1.422 (1.144, 1.772) 0.00161 0.119 (831) 0.137 (835) 0.820 (0.664, 1.013) 0.0667
Combined 0.111 (2736) 0.142 (2738) 0.729 (0.648, 0.820) 1.47E-07 0.138 (2740) 0.116 (2734) 1.287 (1.120, 1.478) 3.87E-05 0.121 (2733) 0.133 (2738) 0.888 (0.792, 0.996) 0.0585
Heterogeneity Q = 0.293, p = 0.588, I2 = 0 Q = 1.194, p = 0.275, I2 = 16.22 Q = 0.834, p = 0.361, I2 = 0
  1. Abbreviations: FTO fat mass and obesity–associated, SE So-Eum, NSE non-So-Eum, TE Tae-Eum, NTE non-Tae-Eum, SY So-Yang, NSY non-So-Yang, MAF minor allele frequency, OR odds ratio, 95% CI, 95% confidence interval.
  2. Logistic regression analysis with adjustment for age and sex in an additive genetic model: (stage 1) genome-wide association analysis in the KoGES population; (stage 2) replication analysis in the KCMS population.
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